dc.contributor.author | Heyer, Robert | |
dc.contributor.author | Schallert, Kay | |
dc.contributor.author | Zoun, Roman | |
dc.contributor.author | Becher, Beatrice | |
dc.contributor.author | Saake, Gunter | |
dc.contributor.author | Benndorf, Dirk | |
dc.date.accessioned | 2019-06-20T01:40:32Z | |
dc.date.available | 2019-06-20T01:40:32Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Heyer, R.; Schallert, K,; Zoun, R.; Becher, B.; Saake, G. and Benndorf, D. (2017) Challenges and perspectives of metaproteomic data analysis. Journal of Biotechnology, 261, pp. 24-36. DOI: https://doi.org/10.1016/j.jbiotec.2017.06.1201. | en_US |
dc.identifier.uri | http://hdl.handle.net/11329/965 | |
dc.identifier.uri | http://dx.doi.org/10.25607/OBP-499 | |
dc.description.abstract | In nature microorganisms live in complex microbial communities. Comprehensive taxonomic and functional
knowledge about microbial communities supports medical and technical application such as fecal diagnostics as
well as operation of biogas plants or waste water treatment plants. Furthermore, microbial communities are
crucial for the global carbon and nitrogen cycle in soil and in the ocean. Among the methods available for
investigation of microbial communities, metaproteomics can approximate the activity of microorganisms by
investigating the protein content of a sample. Although metaproteomics is a very powerful method, issues within
the bioinformatic evaluation impede its success. In particular, construction of databases for protein identification,
grouping of redundant proteins as well as taxonomic and functional annotation pose big challenges.
Furthermore, growing amounts of data within a metaproteomics study require dedicated algorithms and software.
This review summarizes recent metaproteomics software and addresses the introduced issues in detail. | en_US |
dc.language.iso | en | en_US |
dc.rights | Attribution 4.0 | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject.other | Bioinformatics | en_US |
dc.subject.other | Software | en_US |
dc.subject.other | Big data | en_US |
dc.subject.other | Environmental proteomics | en_US |
dc.subject.other | Microbial communities | en_US |
dc.subject.other | Mass spectrometry | en_US |
dc.title | Challenges and perspectives of metaproteomic data analysis. | en_US |
dc.type | Journal Contribution | en_US |
dc.description.refereed | Refereed | en_US |
dc.format.pagerange | pp.24-36 | en_US |
dc.identifier.doi | https://doi.org/10.1016/j.jbiotec.2017.06.1201 | |
dc.subject.parameterDiscipline | Parameter Discipline::Biological oceanography | en_US |
dc.subject.dmProcesses | Data Management Practices::Data archival/stewardship/curation | en_US |
dc.subject.dmProcesses | Data Management Practices::Data format development | en_US |
dc.bibliographicCitation.title | Journal of Biotechnology | en_US |
dc.bibliographicCitation.volume | 261 | en_US |
dc.description.eov | Microbe biomass and diversity | en_US |
dc.description.bptype | Guide | en_US |
obps.contact.contactemail | heyer@mpi-magdeburg.mpg.de | |
obps.resourceurl.publisher | https://www.sciencedirect.com/science/article/pii/S0168165617314979 | en_US |