Biological effects of contaminants: use of liver pathology of the European flatfish dab (Limanda limanda L.) and flounder (Platichthys flesus L.) for monitoring.
Average rating votes
MetadataShow full item record
publication provides quality assurance guidelines for the use of liver pathology of flatfish in biological effects of contaminants monitoring programmes. Information on the sampling procedures, including macroscopic examination, and minimum numbers and size categories of fish required to provide statistical rigour, is included. Details for laboratory processing and staining methods for histological assessment are also given, including protocols for resin embedding. Criteria for the histopathological diagnosis of liver sections are provided under categories on “early non-neoplastic toxicopathic lesions”, “foci of cellular alteration”, “benign neoplasms”, and “malignant neoplasms”, and descriptions of the normal appearance of liver tissue from dab (Limanda limanda) and flounder (Platichthys flesus) are included. More specific criteria are given for the different lesion types occurring in each of these categories. Each lesion type is represented by one or more colour micrographs.....
PublisherInternational Council for the Exploration of the Sea (ICES)
Series;NrICES Techniques in Marine Environmental Sciences;38
Sustainable Development Goals (SDG)14.1
Best Practice TypeStandard Operating Procedure
CitationFeist, S.W.; Lang, T.; Stentifordm G.D., and Köhler, A. (2004) Biological effects of contaminants: Use of liver pathology of the European flatfish dab (Limanda limanda L.) and flounder (Platichthys flesus L.) for monitoring. ICES Techniques in Marine Environmental Sciences, No. 38. 42pp. DOI: http://dx.doi.org/10.25607/OBP-226